Dendrobium Alkaloids

Originally Posted by Ogrestrength

In regards to dendramine, is there any data showing it does anything good at all?

Originally Posted by XXXX

protect the retina and improve eye sight.

Unless we wanted more pea hcl but didnt want more dendrobex.

Originally Posted by Ogrestrength

I couldn't find a single use other then that one of those dilates blood vessels but in turn causues convulsions and is a taurine and beta alanine antagonist.

No hate, just curiosity.

Originally Posted by XXXX

"Dendrobium alkaloids have protective effects against neuronal damage and we confirmed the hypothesis in the present study. This is one of the first studies to investigate the effects of Dendrobium alkaloids on neuronal damage in the presence of OGD/RP. The system of cortical neuron cultures subjected to OGD/RP was used as a model of ischemic cerebrovascular disease, as described previously (Gifford et al., 1993), Dendrobium alkaloids were administrated at different concentrations in order to evaluate the protective role of Dendrobium alkaloids in OGD/RP damaged neurons."

The convulsions were from high doses of pure dendramine IIRC.

Originally Posted by Ogrestrength

That study was performed on rats with oxygen-glucose deprivation and reperfusion. Induced damage essentially. Is there any data backing its effects on healthy users in vivo?

Originally Posted by XXXX

I dont believe dendramine has been studied alone in humans. In the dendramine study you are talking about with regards to convulsions, what was the dose used and what was it studied in?

Originally Posted by Ogrestrength

Rats and rabbits iirc, hold on, updating as I find it, Yea, here it is. Very high dose.

So since neither directly attribute to healthy human consumption, is it a safe assumption that there is no proof it actually has any benefit for the formula?

Originally Posted by XXXX

That study is about dendrobine not dendramine.

Originally Posted by Ogrestrength

Bingo. Because there are none, so, is it a safe assumption that there is no proof it actually has any benefit for the formula?

Also. if you would like to play that game, the abstract you referenced never stated which alkaloids proposed such benefits. As I also doubt it was the 4th and 5th alkaloid as we have established there are no current studies supporting or negating their usage or benefits. So it tends to go in the scrap pile just as mine has been tossed.

Originally Posted by XXXXXXX

Simple reductive logic insists that if the product didn't work, it wouldn't sell. Words are weighed on results.



It's not scientifically feasible to isolate variables so meticulously. We conducted our product development in a controlled environment with safety and performance enhancement in mind. We've tried hundreds of extracts from hundreds of different plants, and we didn't release Craze until we found something extraordinary.

Originally Posted by Ogrestrength

That was in regards to dendramine alone, where as there is no proof of any positive effects.

And the study posted about "dendramine having positive effects on retinas and improving eyesight" was disproven, the study stated "alkaloids", not once was it specified which alkaloids from Dendrobium.

So right now we are running off.......assumptions?

No disrespect to XXXX or you XXXX, these are just questions Ive had bottled up for a while.

Originally Posted by XXXXXXX

No disrespect taken, but it seems your only satisfaction grounds itself in clinical research that doesn't exist.

Originally Posted by Ogrestrength

The same place your proof does.